发明公开
- 专利标题: REMYELINATION USING NEURAL STEM CELLS
- 专利标题(中): 髓鞘再生利用神经干细胞。
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申请号: EP93922482.0申请日: 1993-10-15
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公开(公告)号: EP0664832A1公开(公告)日: 1995-08-02
- 发明人: WEISS, Samuel , REYNOLDS, Brent, A. , HAMMANG, Joseph, P.
- 申请人: NEUROSPHERES LTD.
- 申请人地址: 3330 Hospital Drive N.W. Calgary, Alberta T2N 4N1 CA
- 专利权人: NEUROSPHERES LTD.
- 当前专利权人: NEUROSPHERES LTD.
- 当前专利权人地址: 3330 Hospital Drive N.W. Calgary, Alberta T2N 4N1 CA
- 代理机构: Baldock, Sharon Claire, et al
- 优先权: US19920961813 19921016
- 国际公布: WO1994009119 19940428
- 主分类号: A61K35
- IPC分类号: A61K35 ; A61K38 ; A61P25 ; C07K14 ; C12N5 ; C12N9 ; A61K48
摘要:
A method for the remyelination of neurons is disclosed wherein neural stem cells isolated from adult or fetal neural tissue are proliferated in a culture medium containing a growth factor to produce precursor cells having a nestin (+) phenotype. The precursor cells are capable of differentiation into oligodendrocytes which, when associated with a demyelinated neuron, effect remyelination.
公开/授权文献
- EP0664832B1 REMYELINATION USING NEURAL STEM CELLS 公开/授权日:2002-07-24
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