发明公开
- 专利标题: DYE COMPOSITIONS AND METHODS FOR FILM COATING TABLETS AND THE LIKE
- 专利标题(中): 染料组合物和贴膜工艺用于片剂等
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申请号: EP94903648申请日: 1993-12-14
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公开(公告)号: EP0686031A4公开(公告)日: 1997-07-16
- 发明人: SIGNORINO CHARLES A , MEGGOS HARRY
- 申请人: WARNER JENKINSON CO INC
- 专利权人: WARNER JENKINSON CO INC
- 当前专利权人: WARNER JENKINSON CO INC
- 优先权: US2178593 1993-02-24
- 主分类号: A61K9/28
- IPC分类号: A61K9/28 ; A61K9/34 ; A61K9/36 ; C09B63/00 ; C09B67/46 ; C09D101/02 ; C09D101/08 ; C09D103/00 ; C09D103/02 ; C09D105/00 ; C09D105/02 ; C09D107/00 ; C09D121/00 ; C09D201/00
摘要:
An improved dye composition for use in coating tablets and the like is constituted by a stable, aqueous suspension containing a water-soluble, non-toxic dye, an opacifying agent which may be titanium dioxide or iron oxide, an immobilizing agent for immobilizing the dye and preventing it from migrating when applied to a tablet or the like, the immobilizing agent being constituted by a non-toxic metal salt present in an amount of from approximately 0.1 to 10 equivalents of metal per mole of dye, and water. The suspension may also contain a film-forming, water-soluble or water-dispersible edible polymer and a plasticizer. These compositions are used in lieu of lake compositions to produce tablets and the like with uniform, non-mottled coatings.
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