公开(公告)号：EP0686031A4

公开(公告)日：1997-07-16

申请号：EP94903648

申请日：1993-12-14

申请人： WARNER JENKINSON CO INC

发明人： SIGNORINO CHARLES A ,  MEGGOS HARRY

IPC分类号： A61K9/28 ,  A61K9/34 ,  A61K9/36 ,  C09B63/00 ,  C09B67/46 ,  C09D101/02 ,  C09D101/08 ,  C09D103/00 ,  C09D103/02 ,  C09D105/00 ,  C09D105/02 ,  C09D107/00 ,  C09D121/00 ,  C09D201/00

CPC分类号： A61K9/28

摘要： An improved dye composition for use in coating tablets and the like is constituted by a stable, aqueous suspension containing a water-soluble, non-toxic dye, an opacifying agent which may be titanium dioxide or iron oxide, an immobilizing agent for immobilizing the dye and preventing it from migrating when applied to a tablet or the like, the immobilizing agent being constituted by a non-toxic metal salt present in an amount of from approximately 0.1 to 10 equivalents of metal per mole of dye, and water. The suspension may also contain a film-forming, water-soluble or water-dispersible edible polymer and a plasticizer. These compositions are used in lieu of lake compositions to produce tablets and the like with uniform, non-mottled coatings.