发明公开
EP0687180A1 METHODS FOR DETECTION AND TREATMENT OF INDIVIDUALS HAVING ABNORMAL CELLS EXPRESSING HLA-A2/TYROSINASE PEPTIDE ANTIGENS
失效
方法的检测和治疗具有异常HLA-A2 /酪氨酸酶肽抗原表达细胞的个体
- 专利标题： METHODS FOR DETECTION AND TREATMENT OF INDIVIDUALS HAVING ABNORMAL CELLS EXPRESSING HLA-A2/TYROSINASE PEPTIDE ANTIGENS
- 专利标题（中）： 方法的检测和治疗具有异常HLA-A2 /酪氨酸酶肽抗原表达细胞的个体
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申请号： EP94905393.0申请日： 1993-12-14
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公开(公告)号： EP0687180A1公开(公告)日： 1995-12-20
- 发明人: BOON-FALLEUR, Thierry , BRICHARD, Vincent , VAN PEL, Aline , DE PLAEN, Etienne , COULIE, Pierre , RENAULD, Jean-Christophe , WOLFEL, Thomas , LETHE, Bernard
- 申请人： LUDWIG INSTITUTE FOR CANCER RESEARCH
- 申请人地址： 1345 Avenue of the Americas New York, New York 10105 US
- 专利权人： LUDWIG INSTITUTE FOR CANCER RESEARCH
- 当前专利权人： LUDWIG INSTITUTE FOR CANCER RESEARCH
- 当前专利权人地址： 1345 Avenue of the Americas New York, New York 10105 US
- 代理机构： Bizley, Richard Edward
- 优先权： US19920994928 19921222; US19930054714 19930428; US19930081673 19930623
- 国际公布： WO1994014459 19940707
- 主分类号： C12N15
- IPC分类号： C12N15 ; A61K35 ; A61K38 ; A61K49 ; A61P43 ; C07K7 ; C07K14 ; C07K16 ; C12N5 ; C12N9 ; C12Q1 ; G01N33 ; A61K39 ; A61K48
摘要：
The invention relates to the identification of complexes of human leukocyte antigen molecules and tyrosinase derived peptides on the surfaces of abnormal cells. The therapeutic and diagnostic ramifications of this observation are the subject of the invention.
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