发明公开
- 专利标题: BIOLOGICALLY ACTIVE EPH FAMILY LIGANDS
- 专利标题(中): 生物AKTIVE配体Eph家族的
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申请号: EP95916204.0申请日: 1995-04-04
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公开(公告)号: EP0758381A1公开(公告)日: 1997-02-19
- 发明人: DAVIS, Samuel , GALE, Nicholas , ALDRICH, Thomas H. , MAISONPIERRE, Peter C. , GOLDFARB, Mitchell , YANCOPOULOS, George D.
- 申请人: REGENERON PHARMACEUTICALS, INC.
- 申请人地址: 777 Old Saw Mill River Road Tarrytown, NY 10591-6707 US
- 专利权人: REGENERON PHARMACEUTICALS, INC.
- 当前专利权人: REGENERON PHARMACEUTICALS, INC.
- 当前专利权人地址: 777 Old Saw Mill River Road Tarrytown, NY 10591-6707 US
- 代理机构: Goldin, Douglas Michael, et al
- 优先权: US19940222075 19940404; US19940229402 19940412; US19940299567 19940901; US19940327423 19941021
- 国际公布: WO1995027060 19951012
- 主分类号: C12N15
- IPC分类号: C12N15 ; C07K14 ; C12P21 ; C12R1
摘要:
Novel ligands that bind Eph family receptors are identified, and methods for making the soluble ligands in biologically active form are described. cDNA clones encoding these novel proteins enable production of the recombinant proteins, which are useful to support neuronal and other receptor-bearing cell populations.
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