发明公开
- 专利标题： LOW MOLECULAR WEIGHT PEPTIDOMIMETIC GROWTH HORMONE SECRETAGOGUES
- 专利标题（中）： 小分子多肽于生长激素分泌的步伐
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申请号： EP95940028.0申请日： 1995-11-16
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公开(公告)号： EP0792289A1公开(公告)日： 1997-09-03
- 发明人: SOMERS, Todd, C. , ELIAS, Kathleen, A. , CLARK, Ross, G. , McDOWELL, Robert, S. , STANLEY, Mark, S. , BURNIER, John, P. , RAWSON, Thomas, E.
- 申请人： GENENTECH, INC.
- 申请人地址： 460 Point San Bruno Boulevard South San Francisco, CA 94080-4990 US
- 专利权人： GENENTECH, INC.
- 当前专利权人： GENENTECH, INC.
- 当前专利权人地址： 460 Point San Bruno Boulevard South San Francisco, CA 94080-4990 US
- 代理机构： Kiddle, Simon John, et al
- 优先权： US19940340767 19941116
- 国际公布： WO1996015148 19960523
- 主分类号： C07D295
- IPC分类号： C07D295 ; A61K31 ; A61K38 ; A61P3 ; A61P5 ; C07D209 ; C07D211 ; C07D401 ; C07D403 ; C07K5 ; C07K7 ; C07K14
摘要：
The present invention comprises growth hormone releasing peptides/peptidomimetics (GHRP) capable of causing release of growth hormone from the pituitary. Compositions containing the GHRP's of this invention are used to promote growth in mammals either alone or in combination with other growth promoting compounds, especially IGF-1. In a method of this invention GHRP's in combination with IGF-1 are used to treat Type II diabetes. An exemplary compound (1) of this invention is provided above.
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