发明公开
EP0854870A1 SUBSTITUTED IMIDAZOLES HAVING ANTI-CANCER AND CYTOKINE INHIBITORY ACTIVITY
失效
与癌症REMME SANTANDER和作用CYTOKININHIBIERENDER取代咪唑
- 专利标题： SUBSTITUTED IMIDAZOLES HAVING ANTI-CANCER AND CYTOKINE INHIBITORY ACTIVITY
- 专利标题（中）： 与癌症REMME SANTANDER和作用CYTOKININHIBIERENDER取代咪唑
-
申请号： EP96937654.0申请日： 1996-10-02
-
公开(公告)号： EP0854870A1公开(公告)日： 1998-07-29
- 发明人: SELNICK, Harold, G. , CLAREMON, David, A. , LIVERTON, Nigel, J.
- 申请人： MERCK & CO., INC.
- 申请人地址： 126 East Lincoln Avenue Rahway, New Jersey 07065 US
- 专利权人： MERCK & CO., INC.
- 当前专利权人： MERCK & CO., INC.
- 当前专利权人地址： 126 East Lincoln Avenue Rahway, New Jersey 07065 US
- 代理机构： Thompson, John Dr.
- 优先权： US19950005059P 19951006; US19950005063P 19951006; GB19960002975 19960213; GB19960002907 19960213
- 国际公布： WO1997012876 19970410
- 主分类号： A61K31
- IPC分类号： A61K31 ; A61P7 ; A61P17 ; A61P19 ; A61P29 ; A61P31 ; A61P35 ; A61P37 ; A61P43 ; C07D233 ; C07D401 ; C07D405 ; C07D413 ; C07D417
摘要：
Compounds represented by formula (I), are disclosed. AR represents an aromatic group containing 6-10 atoms; and (a) represents a 4 to 10 membered non-aromatic heterocycle containing at least one N atom, and optionally containing 1-2 additional N atoms and 0-1 O or S atom. A pharmaceutical composition is also included. Methods of treating cancer and cytokine mediated diseases are also included.
公开/授权文献
信息查询
