发明公开
- 专利标题： COMPOUNDS AND METHODS FOR IMMUNOTHERAPY AND DIAGNOSIS OF TUBERCULOSIS
- 专利标题（中）： 化合物和方法免疫治疗和诊断肺结核
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申请号： EP97910873.0申请日： 1997-10-07
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公开(公告)号： EP0932681A2公开(公告)日： 1999-08-04
- 发明人: REED, Steven, G. , SKEIKY, Yasir, A., W. , DILLON, Davin, C. , CAMPOS-NETO, Antonio , HOUGHTON, Raymond , VEDVICK, Thomas, S. , TWARDZIK, Daniel, R. , LODES, Michael, J.
- 申请人： CORIXA CORPORATION
- 申请人地址： 1124 Columbia Street, Suite 464 Seattle, WA 98104 US
- 专利权人： CORIXA CORPORATION
- 当前专利权人： CORIXA CORPORATION
- 当前专利权人地址： 1124 Columbia Street, Suite 464 Seattle, WA 98104 US
- 代理机构： Horner, Martin Grenville, et al
- 优先权： US19960730510 19961011; US19970818112 19970313
- 国际公布： WO1998016646 19980423
- 主分类号： A61K
- IPC分类号： A61K ; C07H ; C07K ; C12N ; G01N ; G01N33 ; A61K39 ; A61K48 ; A61P31 ; C07K14 ; C07K19 ; C12N1 ; C12N5 ; C12N15 ; C12P21 ; C12Q1 ; A61K38
摘要：
Compounds and methods for inducing protective immunity against tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one immunogenic portion of one or more M. tuberculosis proteins and DNA molecules encoding such polypeptides. Such compounds may be formulated into vaccines and/or pharmaceutical compositions for immunization against M. tuberculosis infection, or may be used for the diagnosis of tuberculosis.
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