发明公开
EP0957161A1 METHOD FOR ACTIVATING HUMAN ANTIGEN PRESENTING CELLS, ACTIVATED HUMAN ANTIGEN PRESENTING CELLS, AND USE OF THE SAME
失效
方法激活人力,抗原活化细胞活化的人,抗原活化细胞及其用途
- 专利标题: METHOD FOR ACTIVATING HUMAN ANTIGEN PRESENTING CELLS, ACTIVATED HUMAN ANTIGEN PRESENTING CELLS, AND USE OF THE SAME
- 专利标题(中): 方法激活人力,抗原活化细胞活化的人,抗原活化细胞及其用途
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申请号: EP97949237.8申请日: 1997-12-25
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公开(公告)号: EP0957161A1公开(公告)日: 1999-11-17
- 发明人: KOEZUKA, Y. Kirin Brewery Company, Ltd. , YAMAGUCHI, Y. Kirin Brewery Company, Ltd , MOTOKI, K. Kirin Brewery Company, Ltd.
- 申请人: Kirin Brewery Company, Ltd.
- 申请人地址: 10-1, 2-chome, Shinkawa, Chuo-ku Tokyo 104-8288 JP
- 专利权人: Kirin Brewery Company, Ltd.
- 当前专利权人: Kirin Brewery Company, Ltd.
- 当前专利权人地址: 10-1, 2-chome, Shinkawa, Chuo-ku Tokyo 104-8288 JP
- 代理机构: HOFFMANN - EITLE
- 优先权: JP35042996 19961227
- 国际公布: WO9829534 19980709
- 主分类号: C12N5/22
- IPC分类号: C12N5/22 ; C07H15/04 ; A61K35/14 ; A61K35/28 ; A61K35/36
摘要:
A method for activating human antigen presenting cells characterized by culturing in vitro antigen presenting cells with a human origin together with at least one of glycoside compounds represented by general formula (A) or salts thereof preferably exemplified by (2S, 3S, 4R)-1-(α-D-galactopyranosyloxy)-2-hexacosanoylamino-3,4-octadecanediol; the human antigen presenting cells thus activated; methods for treating cancer or infectious diseases such as AIDS by using activated human antigen presenting cells; and the use of activated human antigen presenting cells in the production of drugs for treating these diseases. Thus, sufficient therapeutic effects can be achieved on cancer and infectious diseases such as AIDS without effecting any pulse therapy with the use of tumor antigens.
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