发明公开
- 专利标题： COMPOSITIONS AND METHODS FOR THE TREATMENT AND DIAGNOSIS OF BREAST CANCER
- 专利标题（中）： 组合物和方法用于治疗和诊断乳腺癌的
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申请号： EP98915351.5申请日： 1998-04-09
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公开(公告)号： EP0975666A2公开(公告)日： 2000-02-02
- 发明人: FRUDAKIS, Tony, N. , SMITH, John, M. , REED, Steven, G.
- 申请人： CORIXA CORPORATION
- 申请人地址： Suite 200,1124 Columbia Street Seattle, WA 98104 US
- 专利权人： CORIXA CORPORATION
- 当前专利权人： CORIXA CORPORATION
- 当前专利权人地址： Suite 200,1124 Columbia Street Seattle, WA 98104 US
- 代理机构： Gowshall, Jonathan Vallance
- 优先权： US838762 19970409; US991789 19971211
- 国际公布： WO9845328 19981015
- 主分类号： C07K14/47
- IPC分类号： C07K14/47 ; C07K14/82 ; C07K14/15 ; C12Q1/68 ; G01N33/574 ; A61K38/17 ; A61K39/00
摘要：
Compositions and methods for the detection and therapy of breast cancer are disclosed. The compounds provided include nucleotide sequences that are preferentially expressed in breast tumor tissue, as well as polypeptides encoded by such nucleotide sequences. Vaccines and pharmaceutical compositions comprising such compounds are also provided and may be used, for example, for the prevention and treatment of breast cancer. The polypeptides may also be used for the production of antibodies, which are useful for diagnosing and monitoring the progression of breast cancer patient.
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