发明公开
- 专利标题： CHIMERIC VACCINE AGAINST TICK-BORNE ENCEPHALITIS VIRUS
- 专利标题（中）： 针对蜱传脑炎病毒嵌合疫苗
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申请号： EP98952184.4申请日： 1998-10-08
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公开(公告)号： EP1021544A2公开(公告)日： 2000-07-26
- 发明人: PLETNEV, Alexander , MEN, Ruhe , CHANOCK, Robert , LAI, Ching-Juh
- 申请人： THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES
- 申请人地址： National Institute of Health,Office of Technology Transfer,6011 Executive Boulevard,Suite 325 Rockville, MD 20852-3804 US
- 专利权人： THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES
- 当前专利权人： THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES
- 当前专利权人地址： National Institute of Health,Office of Technology Transfer,6011 Executive Boulevard,Suite 325 Rockville, MD 20852-3804 US
- 代理机构： VOSSIUS & PARTNER
- 优先权： US61441P 19971008
- 国际公布： WO9918216 19990415
- 主分类号： C12N15/40
- IPC分类号： C12N15/40 ; C07K14/18 ; C12N7/04 ; A61K39/295
摘要：
A live, attenuated chimeric virus vaccine against tick-borne encephalitis virus comprising the preM and E structural genes of the tick-borne encephalitis Langat virus and the non-structural genes of the mosquito-borne dengue virus. The live chimeric vaccine was administered intraperitoneally and exhibited complete attenuation in mice while at the same time providing protection against subsequent challenge with the virulent parental Langat virus.
公开/授权文献
- EP1021544B1 CHIMERIC VACCINE AGAINST TICK-BORNE ENCEPHALITIS VIRUS 公开/授权日：2005-12-28
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