发明公开
- 专利标题： PROCESSES AND INTERMEDIATES USEFUL TO MAKE ANTIFOLATES
- 专利标题（中）： 工艺和中间体用于生产抗叶酸
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申请号： EP99903432.5申请日： 1999-01-27
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公开(公告)号： EP1054859A1公开(公告)日： 2000-11-29
- 发明人: BARNETT, Charles, Jackson , DUNLAP, Steven, Eugene , KOBIERSKI, Michael, Edward , WERNER, John, Arnold
- 申请人： ELI LILLY AND COMPANY
- 申请人地址： Lilly Corporate Center Indianapolis, Indiana 46285 US
- 专利权人： ELI LILLY AND COMPANY
- 当前专利权人： ELI LILLY AND COMPANY
- 当前专利权人地址： Lilly Corporate Center Indianapolis, Indiana 46285 US
- 代理机构： Vaughan, Jennifer Ann
- 优先权： US74327 19980211
- 国际公布： WO9941230 19990819
- 主分类号： C07C255/00
- IPC分类号： C07C255/00 ; C07D207/02 ; C07D211/04 ; C07D213/02 ; C07D231/02 ; C07D231/04 ; C07D231/06 ; C07D231/10 ; C07D233/02 ; C07D233/04 ; C07D233/54
摘要：
The present invention concerns intermediates, and processes directed to and from those intermediates, to a series of pyrimidine derivatives of formula (V), which are intermediates to useful antifolate compounds or are themselves useful antifolate compounds.
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