发明授权
EP1056725B1 INHIBITION OF RAF KINASE USING ARYL AND HETEROARYL SUBSTITUTED HETEROCYCLIC UREAS
有权
RAF激酶的抑制使用芳基 - 和杂芳基的杂环脲类
- 专利标题: INHIBITION OF RAF KINASE USING ARYL AND HETEROARYL SUBSTITUTED HETEROCYCLIC UREAS
- 专利标题(中): RAF激酶的抑制使用芳基 - 和杂芳基的杂环脲类
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申请号: EP98963810.1申请日: 1998-12-22
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公开(公告)号: EP1056725B1公开(公告)日: 2006-06-07
- 发明人: DUMAS, Jacques , KHIRE, Uday , LOWINGER, Timothy, Bruno , RIEDL, Bernd , SCOTT, William, J. , SMITH, Roger, A. , WOOD, Jill, E. , HATOUM-MOKDAD, Holia , JOHNSON, Jeffrey , REDMAN, Aniko , SIBLEY, Robert
- 申请人: Bayer Pharmaceuticals Corp.
- 申请人地址: 400 Morgan Lane West Haven, CT 06516 US
- 专利权人: Bayer Pharmaceuticals Corp.
- 当前专利权人: Bayer Pharmaceuticals Corp.
- 当前专利权人地址: 400 Morgan Lane West Haven, CT 06516 US
- 代理机构: Weiss, Wolfgang
- 优先权: US996181 19971222
- 国际公布: WO1999032455 19990701
- 主分类号: C07D231/38
- IPC分类号: C07D231/38 ; C07D403/12 ; C07D409/12 ; C07D333/36 ; C07D307/66 ; C07D231/40 ; C07D401/12 ; C07D405/04 ; A61K31/415
摘要:
Methods of treating tumors mediated by raf kinase, with substituted urea compounds, and such compounds per se.
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