发明公开
- 专利标题： HUMAN ANTI-FACTOR IX/IXa ANTIBODIES
- 专利标题（中）： HUMANEANTIKÖRPERGEGEN FAKTOR IX / IXA
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申请号： EP99943928.4申请日： 1999-08-26
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公开(公告)号： EP1107996A1公开(公告)日： 2001-06-20
- 发明人: ADAMS, Camellia, W. , DEVAUX, Brigitte , EATON, Dan, L. , HASS, Philip, E. , JUDICE, J., Kevin , KIRCHHOFER, Daniel , SUGGETT, Shelley
- 申请人： Genentech, Inc.
- 申请人地址： 1 DNA Way South San Francisco, CA 94080-4990 US
- 专利权人： Genentech, Inc.
- 当前专利权人： Genentech, Inc.
- 当前专利权人地址： 1 DNA Way South San Francisco, CA 94080-4990 US
- 代理机构： Cripps, Joanna Elizabeth
- 优先权： US98233P 19980828; US122767P 19990303
- 国际公布： WO0012562 20000309
- 主分类号： C07K16/40
- IPC分类号： C07K16/40 ; C12N15/13 ; C12N15/63 ; A61K39/395
摘要：
Human antibodies, or fragments thereof, to the gamma-carboxyglutamic acid (Gla) domain of factor IX and factor IXa, especially of human factor IX and human factor IXa. Isolated nucleic acid encoding said antibodies or fragments thereof. Methods for their preparation. Pharmaceutical composition comprising said antibodies or fragments thereof, and a method for treating a mammal by using said pharmaceutical composition in a therapeutically effective amount.
公开/授权文献
- EP1107996B1 HUMAN ANTI-FACTOR IX/IXa ANTIBODIES 公开/授权日：2002-05-22
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