发明公开
- 专利标题： ISOLATED PEPTIDES WHICH BIND TO HLA-B35 MOLECULES
- 专利标题（中）： 分离的肽对HLA-B35分子结合
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申请号： EP99950142.2申请日： 1999-10-04
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公开(公告)号： EP1123108A1公开(公告)日： 2001-08-16
- 发明人: OOMS, AnnieUniversité de Liège, Sart Tilman , DE GIOVANNI, Gerard,Univ. de Liège, Sart Tilman , MOREL, Sandra , VAN DEN EYNDE, Benoit , BOON-FALLEUR, Thierry
- 申请人： LUDWIG INSTITUTE FOR CANCER RESEARCH
- 申请人地址： 605 Third Avenue New York,New York 10158 US
- 专利权人： LUDWIG INSTITUTE FOR CANCER RESEARCH
- 当前专利权人： LUDWIG INSTITUTE FOR CANCER RESEARCH
- 当前专利权人地址： 605 Third Avenue New York,New York 10158 US
- 代理机构： Hughes, Siân Victoria
- 优先权： US169717 19981009
- 国际公布： WO0021551 20000420
- 主分类号： A61K38/08
- IPC分类号： A61K38/08 ; A61K39/00 ; A61K39/385 ; C12N1/21 ; C12N5/10 ; C12N15/63 ; C12N15/70 ; C12N15/85 ; C12N15/87 ; C12N15/74 ; C07K19/00
摘要：
The invention relates to peptides which bind to HLA-B35 molecules, leading to recognition and lysis of the resulting complexes by cytolytic T cells. Also a part of the invention are nucleic acid molecules which encode these peptides, and uses of each of these. The molecules are derived, in some cases, from tyrosinase, and portions of the tyrosinase molecule and portions of nucleic acid molecules which encode tyrosinase are also a part of the invention.
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