公开(公告)号：EP1123108A1

公开(公告)日：2001-08-16

申请号：EP99950142.2

申请日：1999-10-04

申请人： LUDWIG INSTITUTE FOR CANCER RESEARCH

发明人： OOMS, AnnieUniversité de Liège, Sart Tilman ,  DE GIOVANNI, Gerard,Univ. de Liège, Sart Tilman ,  MOREL, Sandra ,  VAN DEN EYNDE, Benoit ,  BOON-FALLEUR, Thierry

IPC分类号： A61K38/08 ,  A61K39/00 ,  A61K39/385 ,  C12N1/21 ,  C12N5/10 ,  C12N15/63 ,  C12N15/70 ,  C12N15/85 ,  C12N15/87 ,  C12N15/74 ,  C07K19/00

CPC分类号： C12N9/0059 ,  A61K38/00 ,  C07K14/70539

摘要： The invention relates to peptides which bind to HLA-B35 molecules, leading to recognition and lysis of the resulting complexes by cytolytic T cells. Also a part of the invention are nucleic acid molecules which encode these peptides, and uses of each of these. The molecules are derived, in some cases, from tyrosinase, and portions of the tyrosinase molecule and portions of nucleic acid molecules which encode tyrosinase are also a part of the invention.