发明公开
- 专利标题: GENERATION OF VIRTUAL COMBINATORIAL LIBRARIES OF COMPOUNDS
- 专利标题(中): 化合物的生产虚拟组合库
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申请号: EP99921921.5申请日: 1999-05-12
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公开(公告)号: EP1127312A1公开(公告)日: 2001-08-29
- 发明人: GRIFFEY, Richard , SWAYZE, Eric
- 申请人: ISIS PHARMACEUTICALS, INC.
- 申请人地址: 2292 Faraday Avenue Carlsbad, CA 92008 US
- 专利权人: ISIS PHARMACEUTICALS, INC.
- 当前专利权人: ISIS PHARMACEUTICALS, INC.
- 当前专利权人地址: 2292 Faraday Avenue Carlsbad, CA 92008 US
- 代理机构: Hallybone, Huw George
- 优先权: US85092P 19980512; US76405 19980512
- 国际公布: WO9959061 19991118
- 主分类号: G06F9/455
- IPC分类号: G06F9/455
摘要:
Methods for the computer-generation of virtual libraries of compounds are disclosed, including methods for tracking the addition of fragments, use of reagents, and the transformations performed. A tracking table is generated for sample compound C1 and includes entries: (a) listing the order of fragments used, and (b) listing the transformations performed for each synthesis path.
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