发明公开
EP1138775A2 Method of preparing a guanosine-group compound and an intermediate thereof
有权
一种选自鸟苷的制备化合物的方法，以及它们的中间
- 专利标题： Method of preparing a guanosine-group compound and an intermediate thereof
- 专利标题（中）： 一种选自鸟苷的制备化合物的方法，以及它们的中间
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申请号： EP01106745.1申请日： 2001-03-17
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公开(公告)号： EP1138775A2公开(公告)日： 2001-10-04
- 发明人: Mikami, Yoichi , Matsumoto, Seiichiro , Hayashi, Yoshinori , Sato, Toyoki
- 申请人： YUKI GOSEI KOGYO CO., LTD.
- 申请人地址： 10-4, Nihonbashi-Ningyocho 3-chome Chuo-ku Tokyo JP
- 专利权人： YUKI GOSEI KOGYO CO., LTD.
- 当前专利权人： YUKI GOSEI KOGYO CO., LTD.
- 当前专利权人地址： 10-4, Nihonbashi-Ningyocho 3-chome Chuo-ku Tokyo JP
- 代理机构： Dreiss, Fuhlendorf, Steimle & Becker
- 优先权： JP2000087302 20000327
- 主分类号： C12P19/40
- IPC分类号： C12P19/40
摘要：
A glyoxal-guanosine-group compound is prepared either by reacting glyoxal-guanine with any one of ribose-1-phosphate and 2-deoxyribose-1-phosphate in the presence of purine nucleoside phosphorylase, or by reacting glyoxal-guanine with any one selected from the group consisting of uridine, 2'-deoxyuridine and thymidine, together with phosphate ion, in the presence of purine nucleoside phosphorylase and pyrimidine nucleoside phosphorylase. The glyoxal-guanosine-group compound is then decomposed by alkali, whereby a guanosine-group compound consisting of guanosine and 2'-deoxyguanosine is prepared.
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