发明授权
- 专利标题: PTH RECEPTOR AND SCREENING ASSAY UTILIZING THE SAME
- 专利标题(中): PTH受体及测试方法使用相同的
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申请号: EP98965037.9申请日: 1998-12-31
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公开(公告)号: EP1141237B1公开(公告)日: 2005-11-02
- 发明人: GARDELLA, Thomas, J. , KRONENBERG, Henry, M. , POTTS, John, T., Jr.
- 申请人: THE GENERAL HOSPITAL CORPORATION
- 申请人地址: Fruit Street Boston, MA 02114 US
- 专利权人: THE GENERAL HOSPITAL CORPORATION
- 当前专利权人: THE GENERAL HOSPITAL CORPORATION
- 当前专利权人地址: Fruit Street Boston, MA 02114 US
- 代理机构: Chapman, Paul William
- 国际公布: WO2000040698 20000713
- 主分类号: C12N1/21
- IPC分类号: C12N1/21 ; C12N5/10 ; C12N15/12 ; C12N15/63 ; C07K14/72
摘要:
The invention provides a novel PTH receptor polypeptide, r delta Nt, characterized by a deletion of the extracellular amino-terminus, ligand binding domain of the receptor. Additionally disclosed are nucleic acid molecules encoding the receptor. The receptor has a minimal domain for ligand binding and is useful in screening assays designed for the identification of agonists and antagonists of PTH receptor activity.
公开/授权文献
- EP1141237A1 PTH RECEPTOR AND SCREENING ASSAY UTILIZING THE SAME 公开/授权日:2001-10-10
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