发明公开
EP1148122A1 PROCESS FOR PRODUCING HMG-CoA REDUCTASE INHIBITOR
有权
VERFAHREN ZUR HERSTELLUNG EINES HMG-COA REDUKTASE HEMMERS
- 专利标题： PROCESS FOR PRODUCING HMG-CoA REDUCTASE INHIBITOR
- 专利标题（中）： VERFAHREN ZUR HERSTELLUNG EINES HMG-COA REDUKTASE HEMMERS
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申请号： EP00901980.3申请日： 2000-01-28
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公开(公告)号： EP1148122A1公开(公告)日： 2001-10-24
- 发明人: ENDO, Hirofumi , YONETANI, Yoshiyuki , MIZOGUCHI, Hiroshi , HASHIMOTO, Shin-ichi , OZAKI, Akio
- 申请人： KYOWA HAKKO KOGYO CO., LTD.
- 申请人地址： 6-1, Ohtemachi 1-chome Chiyoda-ku, Tokyo 100-8185 JP
- 专利权人： KYOWA HAKKO KOGYO CO., LTD.
- 当前专利权人： KYOWA HAKKO KOGYO CO., LTD.
- 当前专利权人地址： 6-1, Ohtemachi 1-chome Chiyoda-ku, Tokyo 100-8185 JP
- 代理机构： Sternagel, Fleischer, Godemeyer & Partner Patentanwälte
- 优先权： JP2170799 19990129
- 国际公布： WO0044886 20000803
- 主分类号： C12N9/02
- IPC分类号： C12N9/02 ; C12N1/21 ; C12N15/53 ; C12P7/62 ; C12P17/06
摘要：
The present invention relates to a protein derived from a microorganism belonging to the genus Bacillus, which has an activity of hydroxylating a compound represented by the formula (I-a):
wherein R 1 represents a hydrogen atom, a substituted or unsubstituted alkyl, or an alkali metal, and R 2 represents a substituted or unsubstituted alkyl or a substituted or unsubstituted aryl,
or a ring-closed lactone form thereof;
a DNA encoding said protein; and a recombinant DNA comprising said DNA.
wherein R 1 represents a hydrogen atom, a substituted or unsubstituted alkyl, or an alkali metal, and R 2 represents a substituted or unsubstituted alkyl or a substituted or unsubstituted aryl,
or a ring-closed lactone form thereof;
a DNA encoding said protein; and a recombinant DNA comprising said DNA.
公开/授权文献
- EP1148122B1 PROCESS FOR PRODUCING HMG-CoA REDUCTASE INHIBITOR 公开/授权日：2009-09-02
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