发明公开
EP1148127A2 Human G-protein chemokine receptor HDGNR10 (CCR5 receptor). Its uses
失效
Menschlicher G-Protein ChemokinRezepor HDGNR10（CCR5 Rezeptor）。 塞纳Verwendungen
- 专利标题： Human G-protein chemokine receptor HDGNR10 (CCR5 receptor). Its uses
- 专利标题（中）： Menschlicher G-Protein ChemokinRezepor HDGNR10（CCR5 Rezeptor）。 塞纳Verwendungen
-
申请号： EP01108495.1申请日： 1995-06-06
-
公开(公告)号： EP1148127A2公开(公告)日： 2001-10-24
- 发明人: Li, Yi , Ruben, Steven M.
- 申请人： HUMAN GENOME SCIENCES, INC.
- 申请人地址： 9410 Key West Avenue Rockville, MD 20850-3338 US
- 专利权人： HUMAN GENOME SCIENCES, INC.
- 当前专利权人： HUMAN GENOME SCIENCES, INC.
- 当前专利权人地址： 9410 Key West Avenue Rockville, MD 20850-3338 US
- 代理机构： VOSSIUS & PARTNER
- 主分类号： C12N15/12
- IPC分类号： C12N15/12 ; C07K14/715 ; G01N33/68 ; C12Q1/68
摘要：
Human G-protein chemokine receptor polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptides for identifying antagonists and agonists to such polypeptides and methods of using the agonists and antagonists therapeutically to treat conditions related to the underexpression and overexpression of the G-protein chemokine receptor polypeptides, respectively. Also disclosed are diagnostic methods for detecting a mutation in the G-protein chemokine receptor nucleic acid sequences and detecting a level of the soluble form of the receptors in a sample derived from a host.
公开/授权文献
信息查询
IPC分类:
