发明公开
- 专利标题： COMPOUNDS AND METHODS FOR THE DETECTION AND PREVENTION OF $i(T. CRUZI) INFECTION
- 专利标题（中）： 组合物和方法感染克氏锥虫的检测
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申请号： EP00910338.3申请日： 2000-02-24
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公开(公告)号： EP1155322A1公开(公告)日： 2001-11-21
- 发明人: REED, Steven, G. , SKEIKY, Yasir, A., W. , LODES, Michael, J. , HOUGHTON, Raymond, L. , SMITH, John, M. , MCNEILL, Patricia, D.
- 申请人： CORIXA CORPORATION
- 申请人地址： Suite 200,1124 Columbia Street Seattle, WA 98104 US
- 专利权人： CORIXA CORPORATION
- 当前专利权人： CORIXA CORPORATION
- 当前专利权人地址： Suite 200,1124 Columbia Street Seattle, WA 98104 US
- 代理机构： Gowshall, Jonathan Vallance
- 优先权： US256976 19990224
- 国际公布： WO0050897 20000831
- 主分类号： G01N33/569
- IPC分类号： G01N33/569 ; C07K14/44
摘要：
Compounds and methods are provided for diagnosing Trypanosoma cruzi infection. The disclosed compounds are polypeptides, or antibodies thereto, that contain one or more epitopes of T. cruzi antigens. The compounds are useful in a variety of immunoassays for detecting T. cruzi infection. The polypeptide compounds are further useful in vaccines and pharmaceutical compositions for inducing protective immunity against Chagas' disease in individuals exposed to T. cruzi.
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