发明公开
- 专利标题： TYROSINE KINASE RECEPTOR EphA3 ANTIGENIC PEPTIDES
- 专利标题（中）： 酪氨酸激酶受体EphA3的抗原肽
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申请号： EP00910250.0申请日： 2000-02-18
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公开(公告)号： EP1165776A1公开(公告)日： 2002-01-02
- 发明人: CHIARI, Rita , COULIE, Pierre , BOON-FALLEUR, Thierry
- 申请人： LUDWIG INSTITUTE FOR CANCER RESEARCH
- 申请人地址： 605 Third Avenue New York, New York 10158 US
- 专利权人： LUDWIG INSTITUTE FOR CANCER RESEARCH
- 当前专利权人： LUDWIG INSTITUTE FOR CANCER RESEARCH
- 当前专利权人地址： 605 Third Avenue New York, New York 10158 US
- 代理机构： Harrison Goddard Foote
- 优先权： US121170P 19990222; US158566P 19991008
- 国际公布： WO0050589 20000831
- 主分类号： C12N15/12
- IPC分类号： C12N15/12 ; C07K14/47 ; G01N33/566 ; A61K38/17 ; C07K16/28 ; A61K39/395 ; C12N15/62
摘要：
The invention describes HLA class II binding peptides encoded by the EphA3 tumor associated gene, as well as nucleic acids encoding such peptides and antibodies relating thereto. The peptides stimulate the activity and proliferation of CD4+T lymphocytes. Methods and products also are provided for diagnosing and treating conditions characterized by expression of the EphA3 gene.
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