发明公开
EP1175144A2 ORALLY IMMUNOGENIC BACTERIAL ENTEROTOXINS EXPRESSED IN TRANSGENIC PLANTS
审中-公开
中所表达的转基因植物和可口服给药的免疫原性肠细菌
- 专利标题： ORALLY IMMUNOGENIC BACTERIAL ENTEROTOXINS EXPRESSED IN TRANSGENIC PLANTS
- 专利标题（中）： 中所表达的转基因植物和可口服给药的免疫原性肠细菌
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申请号： EP99967556.4申请日： 1999-12-22
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公开(公告)号： EP1175144A2公开(公告)日： 2002-01-30
- 发明人: MASON, Hugh, S. , ARNTZEN, Charles, J.
- 申请人： BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH , Mason, Hugh S. , Arntzen, Charles J.
- 申请人地址： Tower Road Ithaca New York 14853-1801 US
- 专利权人： BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH,Mason, Hugh S.,Arntzen, Charles J.
- 当前专利权人： BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH,Mason, Hugh S.,Arntzen, Charles J.
- 当前专利权人地址： Tower Road Ithaca New York 14853-1801 US
- 代理机构： Maschio, Antonio
- 优先权： US113507P 19981222
- 国际公布： WO0037609 20000629
- 主分类号： A01H1/00
- IPC分类号： A01H1/00 ; A01H1/06 ; A61K39/106 ; A61K39/108 ; C07H21/04 ; C07K14/28 ; C07K14/415 ; C12N5/14 ; C12N15/00
摘要：
The invention provides mutant Escherichia coli heat labile (LT) and Vibrio cholerae toxin (CT) polypeptides and the polynucleotides that encode them. The mutant LT and CT polypeptides can be readily produced in plants and can be used to treat or prevent diseases caused by E. coli and V. cholera. The polypeptides are also useful as adjuvants.
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