发明公开
- 专利标题： AMIDE COMPOUNDS AND MEDICINAL USE THEREOF
- 专利标题（中）： AMID-DERIVATE和DEEN MEDIZINISCHE VERWENDUNG
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申请号： EP00902925申请日： 2000-02-10
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公开(公告)号： EP1176140A4公开(公告)日： 2002-07-31
- 发明人: USHIO HIROYUKI , ISHIBUCHI SEIGO , NAITO YOUICHIRO , SUGIYAMA NAOKI , KAWAGUCHI TAKAFUMI , CHIBA KENJI , OHTSUKI MAKIO , NAKA YOICHI
- 申请人： MITSUBISHI PHARMA CORP
- 专利权人： MITSUBISHI PHARMA CORP
- 当前专利权人： MITSUBISHI PHARMA CORP
- 优先权： JP3336799 1999-02-10; JP19847399 1999-07-13
- 主分类号： A61K31/00
- IPC分类号： A61K31/00 ; A61K31/135 ; A61K31/40 ; A61K45/06 ; A61P29/00 ; A61P37/06 ; A61P43/00 ; C07D207/34 ; C07D231/14 ; C07D401/12 ; C07D401/14 ; C07D403/12 ; C07D405/12 ; C07D409/12 ; C07D491/10 ; C07D491/113 ; A61K31/415 ; A61P37/00 ; C07D231/16 ; C07D231/22 ; C07D521/00
摘要：
Compounds represented by general formula (I) or salts thereof and drugs comprising these compounds wherein R1 represents substituted aryl, heteroaryl, etc.; R?2 and R3¿ represent each hydrogen, alkyl, halogeno, hydroxy, etc.; Q represents N, CH, etc.; W represents hydrogen, alkyl, hydroxycarbonylalkyl, etc.; X represents halogeno, cyano, nitro, amino, etc.; X' represents hydrogen, halogeno, cyano or nitro; and Y represents alkyl, hydroxy, alkoxy, mercapt, etc. Because of having an excellent effect of inhibiting the proliferation of activated lymphocytes, these drugs are useful as preventives or remedies for various autoimmune diseases.
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