发明公开
EP1212323A2 SUBSTITUTED PYRIDINO PENTAAZAMACROCYLE COMPLEXES HAVING SUPEROXIDE DISMUTASE ACTIVITY
有权
取代的吡啶基具有超氧化物歧化酶活性的PENTAAZAMAKROZYKLE COMPLEX
- 专利标题: SUBSTITUTED PYRIDINO PENTAAZAMACROCYLE COMPLEXES HAVING SUPEROXIDE DISMUTASE ACTIVITY
- 专利标题(中): 取代的吡啶基具有超氧化物歧化酶活性的PENTAAZAMAKROZYKLE COMPLEX
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申请号: EP00966722.1申请日: 2000-09-14
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公开(公告)号: EP1212323A2公开(公告)日: 2002-06-12
- 发明人: RILEY, Dennis , NEUMANN, William, L. , HENKE, Susan, L. , LENNON, Patrick , ASTON, Karl, W. , SALVEMINI, Daniela , SIKORSKI, James, A. , FOBIAN, Yvette , GRAPPERHAUS, Margaret, L. , KUSTURIN, Carrie, L.
- 申请人: MONSANTO COMPANY
- 申请人地址: 800 North Lindbergh Boulevard St. Louis, Missouri 63167 US
- 专利权人: MONSANTO COMPANY
- 当前专利权人: MONSANTO COMPANY
- 当前专利权人地址: 800 North Lindbergh Boulevard St. Louis, Missouri 63167 US
- 代理机构: Maiwald, Walter, Dr. Dipl.-Chem.
- 优先权: US398120 19990916
- 国际公布: WO0119823 20010322
- 主分类号: C07D471/08
- IPC分类号: C07D471/08 ; C07D471/06 ; A61K31/555 ; A61P29/00
摘要:
The present invention relates to compounds which are effective as catalysts for dismutating superoxide and, more particularly, the manganese or iron complexes of substituted, unsaturated heterocyclic pentaazacyclopentadecane ligands which catalytically dismutate superoxide.
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