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1.发明授权SUBSTITUTED PYRIDINO PENTAAZAMACROCYLE COMPLEXES HAVING SUPEROXIDE DISMUTASE ACTIVITY 有权取代的吡啶基具有超氧化物歧化酶活性的PENTAAZAMAKROZYKLE COMPLEX
公开(公告)号：EP1212323B1
公开(公告)日：2004-06-09
申请号：EP00966722.1
申请日：2000-09-14
申请人： MONSANTO COMPANY
发明人： RILEY, Dennis , NEUMANN, William, L. , HENKE, Susan, L. , LENNON, Patrick , ASTON, Karl, W. , SALVEMINI, Daniela , SIKORSKI, James, A. , FOBIAN, Yvette , GRAPPERHAUS, Margaret, L. , KUSTURIN, Carrie, L.
IPC分类号： C07D471/08 , C07D471/06 , A61K31/555 , A61P29/00
CPC分类号： C07D471/06 , A61K31/555 , C07D471/08 , C07F13/005 , Y02A50/473
摘要： The present invention relates to compounds which are effective as catalysts for dismutating superoxide and, more particularly, the manganese or iron complexes of substituted, unsaturated heterocyclic pentaazacyclopentadecane ligands which catalytically dismutate superoxide.
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2.发明公开SUBSTITUTED PYRIDINO PENTAAZAMACROCYLE COMPLEXES HAVING SUPEROXIDE DISMUTASE ACTIVITY 有权取代的吡啶基具有超氧化物歧化酶活性的PENTAAZAMAKROZYKLE COMPLEX
公开(公告)号：EP1212323A2
公开(公告)日：2002-06-12
申请号：EP00966722.1
申请日：2000-09-14
申请人： MONSANTO COMPANY
发明人： RILEY, Dennis , NEUMANN, William, L. , HENKE, Susan, L. , LENNON, Patrick , ASTON, Karl, W. , SALVEMINI, Daniela , SIKORSKI, James, A. , FOBIAN, Yvette , GRAPPERHAUS, Margaret, L. , KUSTURIN, Carrie, L.
IPC分类号： C07D471/08 , C07D471/06 , A61K31/555 , A61P29/00
CPC分类号： C07D471/06 , A61K31/555 , C07D471/08 , C07F13/005 , Y02A50/473
摘要： The present invention relates to compounds which are effective as catalysts for dismutating superoxide and, more particularly, the manganese or iron complexes of substituted, unsaturated heterocyclic pentaazacyclopentadecane ligands which catalytically dismutate superoxide.
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