发明公开
- 专利标题: HETEROCYCLIC COMPOUNDS HAVING SULFONAMIDE GROUPS
- 专利标题(中): 杂环化合物的磺酰胺基团
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申请号: EP00985953.9申请日: 2000-12-27
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公开(公告)号: EP1243583A1公开(公告)日: 2002-09-25
- 发明人: HANEDA, Toru , TSURUOKA, Akihiko , KAMATA, Junichi , OKABE, Tadashi , TAKAHASHI, Keiko , NARA, Kazumasa , HAMAOKA, Shinichi , UEDA, Norihiro , WAKABAYASHI, Toshiaki , FUNAHASHI, Yasuhiro , SEMBA, Taro , HATA, Naoko , YAMAMOTO, Yuji , OZAWA, Yoichi , TSUKAHARA, Naoko , OWA, Takashi
- 申请人: Eisai Co., Ltd.
- 申请人地址: 6-10, Koishikawa 4-chome, Bunkyo-ku Tokyo 112-8088 JP
- 专利权人: Eisai Co., Ltd.
- 当前专利权人: Eisai Co., Ltd.
- 当前专利权人地址: 6-10, Koishikawa 4-chome, Bunkyo-ku Tokyo 112-8088 JP
- 代理机构: HOFFMANN - EITLE
- 优先权: JP37548999 19991228
- 国际公布: WO01047891 20010705
- 主分类号: C07D215/38
- IPC分类号: C07D215/38
摘要:
The present invention provides a sulfonamide- or sulfonylurea-containing heterocyclic compounds. Specifically, it provides a heterocyclic compound represented by the formula (I), a pharmacologically acceptable salt thereof or a hydrate of them.
In the formula, A is hydrogen atom, a halogen atom, a C1-C4 alkyl or alkoxy group which may be substituted with a halogen atom, or cyano group; B is an optionally substituted aryl group or monocyclic heteroaryl group, or:
(wherein, the ring Q is an aromatic ring which may have nitrogen atom; and the ring M is a ring sharing a double bond with the ring Q, which ring may have a heteroatom; and the rings Q and M may share nitrogen atom); K is a single bond; T, W, X and Y are the same as or different from each other and each is =C(D)- (wherein, D is hydrogen or a halogen atom) or nitrogen atom; U and V are the same as or different from each other and each is =C(D)-, nitrogen atom, -CH 2 -, oxygen atom or -CO-; Z is a single bond or -CO-NH-; and R 1 is hydrogen atom, etc.
In the formula, A is hydrogen atom, a halogen atom, a C1-C4 alkyl or alkoxy group which may be substituted with a halogen atom, or cyano group; B is an optionally substituted aryl group or monocyclic heteroaryl group, or:
(wherein, the ring Q is an aromatic ring which may have nitrogen atom; and the ring M is a ring sharing a double bond with the ring Q, which ring may have a heteroatom; and the rings Q and M may share nitrogen atom); K is a single bond; T, W, X and Y are the same as or different from each other and each is =C(D)- (wherein, D is hydrogen or a halogen atom) or nitrogen atom; U and V are the same as or different from each other and each is =C(D)-, nitrogen atom, -CH 2 -, oxygen atom or -CO-; Z is a single bond or -CO-NH-; and R 1 is hydrogen atom, etc.
公开/授权文献
- EP1243583B1 HETEROCYCLIC COMPOUNDS HAVING SULFONAMIDE GROUPS 公开/授权日:2005-09-28
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