公开(公告)号：EP1243583A1

公开(公告)日：2002-09-25

申请号：EP00985953.9

申请日：2000-12-27

申请人： Eisai Co., Ltd.

发明人： HANEDA, Toru ,  TSURUOKA, Akihiko ,  KAMATA, Junichi ,  OKABE, Tadashi ,  TAKAHASHI, Keiko ,  NARA, Kazumasa ,  HAMAOKA, Shinichi ,  UEDA, Norihiro ,  WAKABAYASHI, Toshiaki ,  FUNAHASHI, Yasuhiro ,  SEMBA, Taro ,  HATA, Naoko ,  YAMAMOTO, Yuji ,  OZAWA, Yoichi ,  TSUKAHARA, Naoko ,  OWA, Takashi

IPC分类号： C07D215/38

CPC分类号： C07D215/38 ,  C07D215/48 ,  C07D217/02 ,  C07D217/22 ,  C07D217/24 ,  C07D217/26 ,  C07D311/16 ,  C07D401/12 ,  C07D405/12 ,  C07D409/12 ,  C07D411/12 ,  C07D417/12 ,  C07D471/04

摘要： The present invention provides a sulfonamide- or sulfonylurea-containing heterocyclic compounds. Specifically, it provides a heterocyclic compound represented by the formula (I), a pharmacologically acceptable salt thereof or a hydrate of them.
In the formula, A is hydrogen atom, a halogen atom, a C1-C4 alkyl or alkoxy group which may be substituted with a halogen atom, or cyano group; B is an optionally substituted aryl group or monocyclic heteroaryl group, or:
(wherein, the ring Q is an aromatic ring which may have nitrogen atom; and the ring M is a ring sharing a double bond with the ring Q, which ring may have a heteroatom; and the rings Q and M may share nitrogen atom); K is a single bond; T, W, X and Y are the same as or different from each other and each is =C(D)- (wherein, D is hydrogen or a halogen atom) or nitrogen atom; U and V are the same as or different from each other and each is =C(D)-, nitrogen atom, -CH 2 -, oxygen atom or -CO-; Z is a single bond or -CO-NH-; and R 1 is hydrogen atom, etc.

公开(公告)号：EP1243583B1

公开(公告)日：2005-09-28

申请号：EP00985953.9

申请日：2000-12-27

申请人： Eisai Co., Ltd.

发明人： HANEDA, Toru ,  TSURUOKA, Akihiko ,  KAMATA, Junichi ,  OKABE, Tadashi ,  TAKAHASHI, Keiko ,  NARA, Kazumasa ,  HAMAOKA, Shinichi ,  UEDA, Norihiro ,  WAKABAYASHI, Toshiaki ,  FUNAHASHI, Yasuhiro ,  SEMBA, Taro ,  HATA, Naoko ,  YAMAMOTO, Yuji ,  OZAWA, Yoichi ,  TSUKAHARA, Naoko ,  OWA, Takashi

IPC分类号： A61K31/47 ,  A61K31/4709 ,  A61K31/472 ,  A61K31/4725 ,  C07D215/38 ,  C07D215/48 ,  C07D217/22 ,  C07D217/24 ,  C07D217/26 ,  C07D401/12 ,  C07D405/12 ,  C07D409/12 ,  C07D411/12 ,  C07D417/12 ,  A61P19/02 ,  A61P29/00 ,  A61P35/00 ,  A61P35/04

CPC分类号： C07D215/38 ,  C07D215/48 ,  C07D217/02 ,  C07D217/22 ,  C07D217/24 ,  C07D217/26 ,  C07D311/16 ,  C07D401/12 ,  C07D405/12 ,  C07D409/12 ,  C07D411/12 ,  C07D417/12 ,  C07D471/04