发明公开
EP1268543A2 METHODS AND MATERIALS RELATING TO STEM CELL GROWTH FACTOR-LIKE POLYPEPTIDES AND POLYNUCLEOTIDES
审中-公开
材料与方法 - 关于干细胞生长因子样多肽和多核苷酸REFER
- 专利标题: METHODS AND MATERIALS RELATING TO STEM CELL GROWTH FACTOR-LIKE POLYPEPTIDES AND POLYNUCLEOTIDES
- 专利标题(中): 材料与方法 - 关于干细胞生长因子样多肽和多核苷酸REFER
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申请号: EP01932523.2申请日: 2001-04-05
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公开(公告)号: EP1268543A2公开(公告)日: 2003-01-02
- 发明人: TANG, Tom, Y. , LABAT, Ivan , CHAO , Cheng-Chi , MIZE ,Nancy , K. , NISHIKAWA ,Mitsuo , DRMANAC, Radoje, T.
- 申请人: KIRIN BEER KABUSHIKI KAISHA
- 申请人地址: 10-1, Shinkawa 2-Chome, Chuo-Ku,Tokyo JP
- 专利权人: KIRIN BEER KABUSHIKI KAISHA
- 当前专利权人: KIRIN BEER KABUSHIKI KAISHA
- 当前专利权人地址: 10-1, Shinkawa 2-Chome, Chuo-Ku,Tokyo JP
- 代理机构: Richardson, Kate
- 优先权: US543774 20000405; US215733P 20000628; US757562 20010109; US266614P 20010205
- 国际公布: WO01077169 20011018
- 主分类号: C07K14/475
- IPC分类号: C07K14/475 ; C12N15/12 ; C12N5/10 ; A61K38/18 ; C07K16/22 ; C12Q1/68 ; G01N33/53 ; A61K48/00 ; C12N15/22
摘要:
The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human stem cell growth factor-like protein. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries from human testis cells (Hyseq clone identification numbers 2880984 and 2881695, from human fetal skin (Hyseq clone identification number 15375176), adult spleen (Hyseq clone identification number 14856094), and human endothelial cells (Hyseq clone identification numbers 13804756, 13687487, 13804756). Other aspects of the invention include vectors containing processes for producing novel human stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides.
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