发明公开
- 专利标题: METHOD FOR PREPARING MICROPARTICLES HAVING A SELECTED POLYMER MOLECULAR WEIGHT
- 专利标题(中): 用于生产与选定的聚合物分子量微粒
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申请号: EP01928630.1申请日: 2001-04-19
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公开(公告)号: EP1282404A2公开(公告)日: 2003-02-12
- 发明人: WRIGHT, Steven, G. , RICKEY, Michael, E. , RAMSTACK, J., Michael , LYONS, Shawn, L. , HOTZ, Joyce, M.
- 申请人: Alkermes Controlled Therapeutics Inc. II
- 申请人地址: 64 Sidney Street Cambridge, MA 02139-4136 US
- 专利权人: Alkermes Controlled Therapeutics Inc. II
- 当前专利权人: Alkermes Controlled Therapeutics Inc. II
- 当前专利权人地址: 64 Sidney Street Cambridge, MA 02139-4136 US
- 代理机构: Lee, Nicholas John
- 优先权: US575075 20000519
- 国际公布: WO01089482 20011129
- 主分类号: A61K9/16
- IPC分类号: A61K9/16
摘要:
A method for preparing microparticles having a selected polymer molecular weight. The hold time and temperature of a solution containing a nucleophilic compound and a polymer having a starting molecular weight are controlled in order to control the molecular weight of the polymer in the finished microparticle product. In this manner, a selected polymer molecular weight in the finished microparticle product can be achieved from a variety of starting material molecular weights.
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