发明公开
- 专利标题： SUBSTITUTED STILBENES AS GLUCOSE UPTAKE ENHANCERS
- 专利标题（中）： 取代芪葡萄糖录音抑制剂
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申请号： EP01941753.4申请日： 2001-06-01
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公开(公告)号： EP1289936A1公开(公告)日： 2003-03-12
- 发明人: PATTERSON, John , PARK, Jeong, Weong , LUM, Robert, T. , SPEVAK, Wayne, R.
- 申请人： TELIK, INC.
- 申请人地址： 750-H Gateway Boulevard South San Francisco, CA 94080 US
- 专利权人： TELIK, INC.
- 当前专利权人： TELIK, INC.
- 当前专利权人地址： 750-H Gateway Boulevard South San Francisco, CA 94080 US
- 代理机构： Barz, Peter
- 优先权： US208591P 20000602
- 国际公布： WO01094295 20011213
- 主分类号： C07C237/42
- IPC分类号： C07C237/42 ; C07C237/40 ; C07C233/81 ; C07C235/56 ; C07C309/61 ; A61K31/196 ; A61K31/24 ; C07C231/02
摘要：
The present invention relates to chemical compounds, pharmaceutical compositions comprising said compounds, methods of treatment administering these compounds to mammalian hosts, and processes for their preparation. Specifically, the invention relates to a means to enhance insulin-dependent glucose uptake. More specifically, the invention concerns compounds and pharmaceutical compositions that activate the insulin receptor kinase, which leads to increased sensitivity to insulin and an increase in glucose uptake, as well as processes for the preparation of the compounds. The invention also specifically concerns methods for treating humans with hyperglycemia, especially for the treatment of Type II diabetes.
公开/授权文献
- EP1289936B1 SUBSTITUTED STILBENES AS GLUCOSE UPTAKE ENHANCERS 公开/授权日：2004-10-20
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