发明公开
EP1289983A2 HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS
审中-公开
HETEROARYLALKANSÄUREN作为整合受体拮抗剂
- 专利标题： HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS
- 专利标题（中）： HETEROARYLALKANSÄUREN作为整合受体拮抗剂
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申请号： EP01948424.5申请日： 2001-06-15
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公开(公告)号： EP1289983A2公开(公告)日： 2003-03-12
- 发明人: NAGARAJAN, Scrinivasan, Raj , KHANNA, Ish, Kumar , TOLLEFSON, Michael, B. , MOHLER, Scott, B. , CHEN, Barbara , RUSSELL, Mark , DEVADAS, Balekudru , PENNING, Thomas, D. , SCHRETZMAN, Lori, A. , SPANGLER, Dale, P. , BOYS, Mark, Laurence , CHANDRAKUMAR, Nizal, Samuel , LU, Hwang-Fun
- 申请人： Pharmacia Corporation
- 申请人地址： 800 North Lindbergh Boulevard,Mail Zone 04E St. Louis, MO 63167 US
- 专利权人： Pharmacia Corporation
- 当前专利权人： Pharmacia Corporation
- 当前专利权人地址： 800 North Lindbergh Boulevard,Mail Zone 04E St. Louis, MO 63167 US
- 代理机构： Albrecht, Thomas, Dr.
- 优先权： US211781P 20000615; US211782P 20000615
- 国际公布： WO01096334 20011220
- 主分类号： C07D413/12
- IPC分类号： C07D413/12
摘要：
The present invention relates to a class of compounds represented by formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of Formula (I), and methods of selectively antagonizing the αξβ3 and/or the αξβ5 integrin without significantly antagonizing the IIb/IIIa integrin.
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