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EP1292673A2 THROMBOMODULIN ANALOGS FOR PHARMACEUTICAL USE 有权
血栓调节蛋白类似物和它们的药物用途

THROMBOMODULIN ANALOGS FOR PHARMACEUTICAL USE
摘要:
The present invention relates to the design, production and use of analogs of thrombomodulin (TM) that have the ability to enhance the thrombin-mediated activation of protein C but which have a significantly reduced ability to promote activation of thrombin-activatable fibrinolysis inhibitor (TAFI). These analogs are useful in, for example, antithrombotic therapy.
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