发明公开
- 专利标题: ISOLATED NUCLEIC ACID MOLECULES WHICH ENCODE T CELL INDUCIBLE FACTORS, OR INTERLEUKIN-21, THE PROTEINS ENCODED, AND USES THEREOF
- 专利标题(中): 通过IL-TIF调制/白细胞介素-21
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申请号: EP01952260.6申请日: 2001-06-27
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公开(公告)号: EP1305419A2公开(公告)日: 2003-05-02
- 发明人: DUMOUTIER, Laure , RENAULD, Jean-Christophe
- 申请人: LUDWIG INSTITUTE FOR CANCER RESEARCH
- 申请人地址: 605 Third Avenue New York,New York 10158 US
- 专利权人: LUDWIG INSTITUTE FOR CANCER RESEARCH
- 当前专利权人: LUDWIG INSTITUTE FOR CANCER RESEARCH
- 当前专利权人地址: 605 Third Avenue New York,New York 10158 US
- 代理机构: Brasnett, Adrian Hugh
- 优先权: US626617 20000727
- 国际公布: WO02010393 20020207
- 主分类号: C12N15/24
- IPC分类号: C12N15/24 ; C12N15/63 ; C07K14/54 ; G01N33/50
摘要:
The invention involves isolation of nucleic acid molecules, the expression of which are upregulated by interleukin-9. The amino acid sequences of the proteins which correspond to the nucleic acid molecules show some structural features of cytokines. In addition to the nucleic acid molecules and the proteins, various uses of the molecules are disclosed. The molecules are referred to as T cell inducible factors. The molecules are implicated in activation of STAT molecules, acute phase proteins, and inflammation.
公开/授权文献
- EP1305419B1 MODULATION BY IL-TIF/INTERLEUKIN-21 公开/授权日:2007-06-27
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