发明公开
- 专利标题： "PSEUDO"-NATIVE CHEMICAL LIGATION
- 专利标题（中）： “PSEUDO”-NATIVE CHEMISCHE LIGATION
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申请号： EP01952657.3申请日： 2001-07-12
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公开(公告)号： EP1315513A2公开(公告)日： 2003-06-04
- 发明人: KENT, Stephen, B., H. , BOTTI, Paolo , LOW, Donald, W. , BRADBURNE, James, A. , HUNTER, Christie, L. , CHEN, Shiah-yun , CRESSMAN, Sonya , KOCHENDOERFER, Gerd
- 申请人： Gryphon Therapeutics, Inc.
- 申请人地址： 250 East Grand Avenue South San Francisco, CA 94080-4824 US
- 专利权人： Gryphon Therapeutics, Inc.
- 当前专利权人： Gryphon Therapeutics, Inc.
- 当前专利权人地址： 250 East Grand Avenue South San Francisco, CA 94080-4824 US
- 代理机构： Micheli & Cie
- 优先权： US231339P 20000908; US236377P 20000929
- 国际公布： WO02020034 20020314
- 主分类号： A61K38/02
- IPC分类号： A61K38/02 ; A61K38/18 ; A61K38/19 ; A61K38/20 ; A61K38/21 ; A61K38/27 ; C07K1/02 ; C07K2/00 ; C07K14/475 ; C07K14/505 ; C07K14/52 ; C07K14/525 ; C07K14/535 ; C07K14/54 ; C07K14/555 ; C07K14/575
摘要：
The present invention concerns methods and compositions for extending the technique of native chemical ligation of a wider range of peptides, polypeptides, other polymers and other molecules via an amide bond (see Figure 1). The invention further provides methods and uses for such proteins and derivatized proteins. The invention is particularly suitable for use in the synthesis of optionally polymer-modified, synthetic bioactive proteins, and of pharmaceutical compositions that contain such proteins.
公开/授权文献
- EP1315513B1 "PSEUDO"-NATIVE CHEMICAL LIGATION 公开/授权日：2011-03-09
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