发明授权
- 专利标题: STEM CELL DIFFERENTIATION-INDUCING PROMOTER
- 专利标题(中): STEMZELLDIFFERENZIERUNG INDUZIERENDE促销商
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申请号: EP01972471.5申请日: 2001-09-19
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公开(公告)号: EP1322748B1公开(公告)日: 2009-12-02
- 发明人: LUU, Bang, Chimie Subst. Nat., ULP-CNRS UMR 7123 , MOHIER, Eliane, Chimie S. Nat., ULP-CNRS UMR 7123 , YAMADA, Masashi, c/o Meiji Dairies Corp. , SUMA, Yukie, c/o Meiji Dairies Corp. , SUZUKI, Hiroto, c/o Meiji Dairies Corp.
- 申请人: Meiji Dairies Corporation
- 申请人地址: 2-10, Shin-suna 1-chome Koto-ku, Tokyo 136-8908 JP
- 专利权人: Meiji Dairies Corporation
- 当前专利权人: Meiji Dairies Corporation
- 当前专利权人地址: 2-10, Shin-suna 1-chome Koto-ku, Tokyo 136-8908 JP
- 代理机构: Wächtershäuser, Günter
- 优先权: JP2000304746 20001004
- 国际公布: WO2002029014 20020411
- 主分类号: C12N5/08
- IPC分类号: C12N5/08 ; A61K31/122 ; A61K35/12 ; A61P25/00 ; C07C50/28
摘要:
Provided is a stem-cell differentiation and induction promoter, which comprises as an effective ingredient a cyclohexenone long-chain alcoholic derivative represented by the formula (1):[wherein, R?1, R2 and R3¿ each independently represents a hydrogen atom or a methyl group and X represents a linear or branched C10-28 alkylene or alkenylene group]. Since the cyclohexenone long-chain alcoholic derivative according to the present invention promotes differentiation-induction of stem cells into cells expressing a specific biological function, a medicament comprising the derivative is useful as a preventive or remedial drug for diseases such as nervous diseases, bone diseases, circulatory diseases and myopathy, caused by the degeneration of tissues or cells or cell death.
公开/授权文献
- EP1322748A2 STEM CELL DIFFERENTIATION-INDUCING PROMOTER 公开/授权日:2003-07-02
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