发明公开
EP1328638A2 SECRETED ALPHA-HELICAL PROTEIN ZLMDA24
审中-公开
SEKRETIERTES ALPHA-HELICALES CYTOKIN-ÄHNLICHESPROTEIN ZLMDA24
- 专利标题: SECRETED ALPHA-HELICAL PROTEIN ZLMDA24
- 专利标题(中): SEKRETIERTES ALPHA-HELICALES CYTOKIN-ÄHNLICHESPROTEIN ZLMDA24
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申请号: EP01988513.6申请日: 2001-10-19
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公开(公告)号: EP1328638A2公开(公告)日: 2003-07-23
- 发明人: CONKLIN, Darrell, C. , GAO, Zeren , LOFTON-DAY, Catherine, E. , WHITMORE, Theodore, E.
- 申请人: ZymoGenetics, Inc.
- 申请人地址: 1201 Eastlake Avenue East Seattle, WA 98102 US
- 专利权人: ZymoGenetics, Inc.
- 当前专利权人: ZymoGenetics, Inc.
- 当前专利权人地址: 1201 Eastlake Avenue East Seattle, WA 98102 US
- 代理机构: Schlich, George William
- 优先权: US242023P 20001020
- 国际公布: WO02034917 20020502
- 主分类号: C12N15/24
- IPC分类号: C12N15/24 ; C07K14/52
摘要:
The present invention relates to zlmda24 polynucleotide and polypeptide molecules. Zlmda24 is a novel cytokine-like polypeptide with an anti-parallel alphahelical structure. The polypeptides may be used within methods for stimulating the proliferation and/or development of hematopoietic cells in vitro and in vivo. Moreover, zlmda24 polynucleotides, polypeptides and antibodies can be used as a diagnostic to detect the presence of human testis tissue. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.
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