发明公开
- 专利标题: INFLAMMATION RELATED G-PROTEIN COUPLED RECEPTOR
- 专利标题(中): 一个ENTZÜNDUNGSVERWANDTERG蛋白偶联受体
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申请号: EP01980246.1申请日: 2001-08-16
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公开(公告)号: EP1364017A2公开(公告)日: 2003-11-26
- 发明人: JARAI, Gabor,Novartis Horsham Research Centre , YOUSEFI, Shida
- 申请人: Novartis AG , Novartis Pharma GmbH
- 申请人地址: Lichtstrasse 35 4002 Basel CH
- 专利权人: Novartis AG,Novartis Pharma GmbH
- 当前专利权人: Novartis AG,Novartis Pharma GmbH
- 当前专利权人地址: Lichtstrasse 35 4002 Basel CH
- 代理机构: Gros, Florent
- 优先权: US641653 20000818
- 国际公布: WO02013845 20020221
- 主分类号: C12N15/12
- IPC分类号: C12N15/12 ; C07K14/705 ; C12N15/11 ; C07K16/28 ; G01N33/50 ; A61K39/395 ; A61K38/17 ; A61K31/7105
摘要:
A pharmaceutical composition comprising as active ingredient (A) a polypeptide comprising the amino acid sequence of SEQ ID NO:2 or SEQ ID NO:16 or a functionally equivalent variant of said amino acid sequence; or (B) a polynucleotide comprising a nucleotide sequence encoding the polypeptide (A); or (C) an antibody which is immunoreactive with the polypeptide (A); or (D) an antisense oligonucleotide comprising a nucleotide sequence complementary to that of polynucleotide (B); and the use of (A), (B), (C) and (D) in diagnostic and therapeutic applications.
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