发明公开
EP1397516A4 ANTISENSE MODULATION OF INTERLEUKIN 12 P40 SUBUNIT EXPRESSION
审中-公开
表达白细胞介素12 p40亚单位的反义调节
- 专利标题： ANTISENSE MODULATION OF INTERLEUKIN 12 P40 SUBUNIT EXPRESSION
- 专利标题（中）： 表达白细胞介素12 p40亚单位的反义调节
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申请号： EP02746328申请日： 2002-05-01
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公开(公告)号： EP1397516A4公开(公告)日： 2005-05-11
- 发明人: BAKER BRENDA F , FREIER SUSAN M
- 申请人： ISIS PHARMACEUTICALS INC
- 专利权人： ISIS PHARMACEUTICALS INC
- 当前专利权人： ISIS PHARMACEUTICALS INC
- 优先权： US85106201 2001-05-07
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C12N15/113 ; C12Q1/68 ; C07H21/04 ; C12N15/85
摘要：
Antisense compounds, compositions and methods are provided for modulating the expression of Interleukin 12 p40 subunit. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Interleukin 12 p40 subunit. Methods of using these compounds for modulation of Interleukin 12 p40 subunit expression and for treatment of diseases associated with expression of Interleukin 12 p40 subunit are provided.
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