发明公开
EP1400533A1 HASylated polypeptides, especially HASylated erythropoietin
审中-公开
Hasylierte多肽,尤其是促红细胞生成素hasyliertes
- 专利标题: HASylated polypeptides, especially HASylated erythropoietin
- 专利标题(中): Hasylierte多肽,尤其是促红细胞生成素hasyliertes
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申请号: EP02020425.1申请日: 2002-09-11
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公开(公告)号: EP1400533A1公开(公告)日: 2004-03-24
- 发明人: Conradt, Harald S. , Grabenhorst, Eckart , Nimtz, Manfred , Zander, Norbert , Frank, Ronald , Eichner, Wolfram
- 申请人: Fresenius Kabi Deutschland GmbH
- 申请人地址: Kabi Strategic Business Center 61346 Bad Homburg v.d.H. DE
- 专利权人: Fresenius Kabi Deutschland GmbH
- 当前专利权人: Fresenius Kabi Deutschland GmbH
- 当前专利权人地址: Kabi Strategic Business Center 61346 Bad Homburg v.d.H. DE
- 代理机构: Wichmann, Hendrik, Dr.
- 主分类号: C07K14/505
- IPC分类号: C07K14/505 ; C07K17/10 ; C08B31/00 ; C07K17/06 ; C12N15/12 ; A61K38/18 ; C07K14/55 ; C07K14/54 ; C07K14/56 ; C07K14/565 ; C07K14/53
摘要:
The present invention relates to hydroxyalkylstarch (HAS)-polypeptide-conjugate (HAS-polypeptide) comprising one or more HAS moecules, wherein each HAS is conjugated to the polypeptide via a carbohydrate moiety or a thioether as well as to methods for the production thereof. In a preferred embodiment, the polypeptide is erythropoietin (EPO).
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