发明公开
- 专利标题: NEW INDOLE DERIVATIVES WITH 5-HT6 RECEPTOR AFFINITY
- 专利标题(中): 用亲和对5-HT 6受体的新的吲哚衍生物
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申请号: EP02735394.5申请日: 2002-05-29
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公开(公告)号: EP1401813A1公开(公告)日: 2004-03-31
- 发明人: BEARD, Colin, Charles , CLARK, Robin, Douglas , FISHER, Lawrence, Emerson , HARRIS, Ralph, New, III , REPKE, David, Bruce
- 申请人: F. Hoffman-la Roche AG
- 申请人地址: 124 Grenzacherstrasse 4070 Basle CH
- 专利权人: F. Hoffman-la Roche AG
- 当前专利权人: F. Hoffman-la Roche AG
- 当前专利权人地址: 124 Grenzacherstrasse 4070 Basle CH
- 代理机构: Wächter, Dieter Ernst, Dr.
- 优先权: US296705P 20010607; US340212P 20011213
- 国际公布: WO2002098857 20021212
- 主分类号: C07D209/30
- IPC分类号: C07D209/30 ; A61K31/496 ; C07D403/04 ; A61P25/00
摘要:
This invention relates to compounds which have generally 5-HT6 receptor affinity and which are represented by Formula (I), wherein one of R?5, R6 or R7¿ is a group of general Formula (B), wherein W is a -CH-group or a nitrogen atom, and the other substituents are as defined herein; or individual isomers, racemic or non-racemic mixtures of isomers, or pharmaceutically aceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing such compounds, Their use as therapeutic agents, and methods of preparation thereof.
公开/授权文献
- EP1401813B1 NEW INDOLE DERIVATIVES WITH 5-HT6 RECEPTOR AFFINITY 公开/授权日:2007-02-07
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