Compounds represented by the general formula (I) or salts or prodrugs thereof are excellent in neurodegeneration inhibiting activity and migration toward the brain, have low toxicity, and are useful as preventive and therapeutic agents for neurodegenerative diseases: (I) wherein R1 and R2 are each independently hydrogen, a hydrocarbon group, or a heterocyclic group, or R1 and R2 together with the carbon atom adjacent thereto may form a 3- to 8-membered homo- or hetero-cycle; R3 is a cyclic group, hydroxyl, optionally oxo-modified mercapto, or amino; R4 is hydrogen, a hydrocarbon group, hydroxyl, optionally oxo-modified mercapto, or amino, or R2 and R4 may be united to form a double bond; X is a free valency or a linear hydrocarbon group; W is oxygen or sulfur; B is a 5- to 8-membered nitrogenous heterocycle; C is a benzene ring; and the symbol ... represents a single or double bond.