发明公开
- 专利标题: INHIBITION OF APOPTOSIS PROCESS AND IMPROVEMENT OF CELL PERFORMANCE
- 专利标题(中): 细胞凋亡过程的抑制和改善电池性能
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申请号: EP02742400.1申请日: 2002-07-10
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公开(公告)号: EP1414948A2公开(公告)日: 2004-05-06
- 发明人: REFF, Mitchell , BETENBAUGH, Michael, J. , FIGUEROA, Bruno, Jr. , AILOR, Eric , HARDWICK, Marie
- 申请人: Idec Pharmaceuticals Corporation
- 申请人地址: 3030 Callan Road San Diego, CA 92121 US
- 专利权人: Idec Pharmaceuticals Corporation
- 当前专利权人: Idec Pharmaceuticals Corporation
- 当前专利权人地址: 3030 Callan Road San Diego, CA 92121 US
- 代理机构: VOSSIUS & PARTNER
- 优先权: US303813P 20010710
- 国际公布: WO2003006607 20030123
- 主分类号: C12N5/10
- IPC分类号: C12N5/10 ; C12N5/06 ; C12N5/08 ; C12P21/00 ; C07H21/00 ; C07K14/00
摘要:
The present invention relates to preventing or delaying programmed cell death by expressing one or more anti-apoptotic polypeptides in a cell such that programmed cell death in the cell is prevented or delayed. The present invention also relates to increasing production of a cell-related product by expressing one or more anti-apoptotic polypeptides in a cell such that production of the cell-related product by the cell is increased. Recombinant cells useful for producing cell-related product or cellular therapy are also provided.
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