发明公开
EP1416051A1 PROCESS FOR PRODUCING NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (NADP)
有权
维生素Zur Herstellung von Nikotinamid-Adinin-Dinukleotid-Phosphat（NADP）
- 专利标题： PROCESS FOR PRODUCING NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (NADP)
- 专利标题（中）： 维生素Zur Herstellung von Nikotinamid-Adinin-Dinukleotid-Phosphat（NADP）
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申请号： EP02738905.5申请日： 2002-07-02
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公开(公告)号： EP1416051A1公开(公告)日： 2004-05-06
- 发明人: KAWAI, Shigeyuki , MURATA, Kousaku , MATSUKAWA, Hirokazu, c/o Oriental Yeast Co., Ltd. , TOMISAKO, Shoichi, c/o Oriental Yeast Co., Ltd. , ANDO, Yoshio, c/o Oriental Yeast Co., Ltd. , MATSUO, Yuhsi, c/o Oriental Yeast Co., Ltd.
- 申请人： ORIENTAL YEAST CO., LTD.
- 申请人地址： 6-10, Azusawa 3-chome Itabashi-ku Tokyo 174-8505 JP
- 专利权人： ORIENTAL YEAST CO., LTD.
- 当前专利权人： ORIENTAL YEAST CO., LTD.
- 当前专利权人地址： 6-10, Azusawa 3-chome Itabashi-ku Tokyo 174-8505 JP
- 代理机构： HOFFMANN - EITLE
- 优先权： JP2001201400 20010702
- 国际公布： WO2003004654 20030116
- 主分类号： C12N15/54
- IPC分类号： C12N15/54 ; C12P19/36
摘要：
The present invention provides a novel process for preparing nicotinamide adenine dinucleotide phosphate (NADP). The process of the present invention comprises performing phosphorylation using a polyphosphoric acid or a salt thereof and nicotinamide adenine dinucleotide (NAD + ) as substrates in the presence of a polyphosphate-dependent NAD + kinase from a Mycobacterium, wherein the reaction solution contains 0.1-15% by weight of the polyphosphoric acid or a salt thereof, and 5-150 mM of a divalent metal ion.
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