发明公开
- 专利标题： PYRAZOLE-DERIVED KINASE INHIBITORS AND USES THEREOF
- 专利标题（中）： 吡唑衍生的激酶抑制剂及其用途
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申请号： EP02791565.1申请日： 2002-08-02
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公开(公告)号： EP1423380A1公开(公告)日： 2004-06-02
- 发明人: TANG, Qing , MALTAIS, Francois , JANETKA, James, Walter , HALE, Michael, Robin
- 申请人： VERTEX PHARMACEUTICALS INCORPORATED
- 申请人地址： 130 Waverly Street Cambridge, MA 02139-4242 US
- 专利权人： VERTEX PHARMACEUTICALS INCORPORATED
- 当前专利权人： VERTEX PHARMACEUTICALS INCORPORATED
- 当前专利权人地址： 130 Waverly Street Cambridge, MA 02139-4242 US
- 代理机构： VOSSIUS & PARTNER
- 优先权： US309886P 20010803
- 国际公布： WO2003011854 20030213
- 主分类号： C07D401/04
- IPC分类号： C07D401/04 ; C07D405/14 ; C07D401/14 ; C07D403/14 ; C07D413/14 ; A61K31/4155 ; A61K31/4439 ; A61P35/00 ; A61P29/00
摘要：
Described herein are compounds that are useful as protein kinase inhibitors having the formula: (1) , where B, R?l, n, R3¿, Q, and R4 are described in the specification. The compounds are useful for treating disease states in mammals that are alleviated by a protein kinase inhibitor, particularly diseases such as cancer, inflammatory disorders, restenosis, and cardiovascular disease.
公开/授权文献
- EP1423380B1 PYRAZOLE-DERIVED KINASE INHIBITORS AND USES THEREOF 公开/授权日：2010-12-15
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