发明公开
- 专利标题: ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR DELTA
- 专利标题(中): 激活剂过氧化物酶体增殖响应受体δ
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申请号: EP02755779申请日: 2002-08-02
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公开(公告)号: EP1424330A4公开(公告)日: 2004-10-27
- 发明人: SAKUMA SHOGO , YAMAKAWA TOMIO , KANDA TAKASHI , MASUI SEIICHIRO
- 申请人: NIPPON CHEMIPHAR CO
- 专利权人: NIPPON CHEMIPHAR CO
- 当前专利权人: NIPPON CHEMIPHAR CO
- 优先权: JP2001243734 2001-08-10
- 主分类号: A61P3/04
- IPC分类号: A61P3/04 ; A61P3/06 ; A61P3/10 ; A61P5/14 ; A61P9/00 ; A61P9/10 ; A61P19/10 ; A61P21/04 ; A61P25/28 ; A61P31/00 ; A61P35/00 ; A61P43/00 ; C07D233/54 ; C07D263/32 ; C07D263/62 ; C07D277/24 ; C07D277/26 ; A61K31/421 ; A61K31/426
摘要:
A compound represented by the following general formula (I): (I) (wherein R1 represents optionally substituted phenyl, etc.; R2 represents C1-8 alkyl, etc.; A represents oxygen, etc.; X represents a C1-8 alkylene chain, etc.; Y represents C(=O), etc.; R3, R4, and R5 each represents hydrogen, C1-8 alkyl, etc.; B represents CH, etc.; Z represents oxygen or sulfur; R6 and R7 each represents hydrogen, etc.; and R8 represents hydrogen, etc.; provided that at least one of R3, R4, and R5 is not hydrogen) or a salt of the compound; and a PPAR-δ activator which contains the compound or salt as the active ingredient.
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