Methods of producing a photosensitive ceramic composition and a multi-layer substrate using it. The ceramic multi-layer substrate and the production method therefor are applicable to circuit materials and components for high-frequency radio-use ceramic multi-layer substrate. A photosensitive ceramic composition comprising inorganic powder and a photosensitive organic component as essential components, characterized in that at least part of the surface of the inorganic powder is formed with a portion consisting of an inorganic material lower in refractive index than the inner layer portion of the inorganic power.