发明公开
- 专利标题： BENZIMIDAZOLES USEFUL AS PROTEIN KINASE INHIBITORS
- 专利标题（中）： FOR USE的苯并咪唑作为蛋白激酶抑制剂
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申请号： EP02789445.0申请日： 2002-11-05
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公开(公告)号： EP1448199A1公开(公告)日： 2004-08-25
- 发明人: CYWIN, C.,Boehringer Ingelheim Pharma., Inc. , LEE, J.,Boehringer Ingelheim Pharma., Inc. , ROTH, G. P.,Boehringer Ingelheim Pharma., Inc. , SARKO, C. R.,Boehringer Ingelheim Pharma., Inc. , SNOW, R. J.,Boehringer Ingelheim Pharma., Inc. , WILSON, N. S.,Boehringer Ingelheim Pharma., Inc. , PULLEN, S. S.,Boehringer Ingelheim Pharma., Inc.
- 申请人： BOEHRINGER INGELHEIM PHARMACEUTICALS INC.
- 申请人地址： 900 Ridgebury Road,P.O. Box 368 Ridgefield,Connecticut 06877-0368 US
- 专利权人： BOEHRINGER INGELHEIM PHARMACEUTICALS INC.
- 当前专利权人： BOEHRINGER INGELHEIM PHARMACEUTICALS INC.
- 当前专利权人地址： 900 Ridgebury Road,P.O. Box 368 Ridgefield,Connecticut 06877-0368 US
- 代理机构： Hammann, Heinz, Dr.
- 优先权： US344636P 20011109
- 国际公布： WO2003041708 20030522
- 主分类号： A61K31/4439
- IPC分类号： A61K31/4439 ; A61K31/422 ; A61K31/4184 ; C07D409/12 ; C07D401/12 ; C07D413/12 ; C07D407/12 ; C07D235/30
摘要：
Disclosed are substituted benzimidazole compounds of formula (I) wherein R1, R2, R3, R4 and Xa are defined herein. The compounds of the invention are useful for treating diseases and pathological conditions involving inflammation, immunological disorders and allergic disorders. Also disclosed are processes for preparing these compounds and to pharmaceutical compositions comprising these compounds.
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