发明公开
EP1453500A1 STYRYL ACRYLONITRILE COMPOUNDS AND THEIR USE TO PROMOTE MYELOPOIESIS
审中-公开
苯乙烯 - 丙烯腈衍生物及其促进髓
- 专利标题： STYRYL ACRYLONITRILE COMPOUNDS AND THEIR USE TO PROMOTE MYELOPOIESIS
- 专利标题（中）： 苯乙烯 - 丙烯腈衍生物及其促进髓
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申请号： EP02767023.1申请日： 2002-10-11
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公开(公告)号： EP1453500A1公开(公告)日： 2004-09-08
- 发明人: ROIFMAN, Chaim, M. , GRUNBERGER, Thomas , SHARFE, Nigel , ROUNOVA, Olga B. , DEMIN, Peter M. , FREYWALD, Andrew
- 申请人： THE HOSPITAL FOR SICK CHILDREN
- 申请人地址： Research Institute,555 University Avenue TorontoOntario M5G 1X8 CA
- 专利权人： THE HOSPITAL FOR SICK CHILDREN
- 当前专利权人： THE HOSPITAL FOR SICK CHILDREN
- 当前专利权人地址： Research Institute,555 University Avenue TorontoOntario M5G 1X8 CA
- 代理机构： Mallalieu, Catherine Louise
- 优先权： US329168P 20011011
- 国际公布： WO2003030895 20030417
- 主分类号： A61K31/277
- IPC分类号： A61K31/277 ; A61P15/06
摘要：
The invention relates to the use of organic compounds, styryl acrylonitrile compounds to promote myelopoiesis. These compounds thefore may be used to treat a subject suffering from neutropenia and other conditions which would benefit from increased myelopoieses. Moreover, the compounds may be used to treat hematopoietic cells ex-vivo to promote myelopoiesis and therefore may be used advantageously in bone marrow or peripheral blood stem cell transplant.
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